5 nm and 3 nm functionalized gold nanoparticles are available with a range of solubility properties:
hydrophilic, hydrophobic, and amphiphilic.
These nanoparticles are coated and stabilized using different
thiol ligands capped by chemical groups which provide a variety of solubilities, and these gold
nanomaterials are therefore suitable for a wide range of applications in different systems and
The octane- and dodecanethiol functionalized gold nanoparticles have great solubility in
organic solvent such as toluene, while the hydrophilic (1-mercaptoundec-11-yl) tetraethyleneglycol
functionalized gold nanoparticles dissolve in water and alcohols. The 1-mercapto-(triethyleneglycol)
methyl ester functionalized gold nanoparticles are amphiphilic, dissolving in a wide variety of solvents
including toluene, chloroform, ethyl acetate, acetone, water and alcohols.